Osicent 80: Each tablet contains a dose of osimertinib mesylate equivalent to 80 mg osimertinib.
Osicent is an epidermal growth factor receptor (EGFR) kinase inhibitor that binds irreversibly to some mutant forms of EGFR. In cultured cells and animal tumor implantation models, osimertinib had anti-tumor effects in non-small cell lung cancer (NSCLC).
80 mg orally once a day, with or without food.
Among the most common (> 20%) adverse reactions (all classes) observed in people treated with Osicent 80 were diarrhea (42%), rash (41%), dry skin (31%) and brittle nails (25%) ). Serious adverse reactions reported in 2% or more of patients were caused by pneumonia and pulmonary embolism.
Based on its mechanism of action and animal data, Osimertinib may cause fetal harm when used by a pregnant woman. There are no data on the use of Osicent in pregnant women. Pregnant women should be apprised of the potential risk to the fetus.
There are no data available on the presence of Osicent in human milk, on the effect on a nursing infant or on milk production. During treatment, a nursing mother is advised not to breastfeed.
The safety and efficacy of Osicent in children has not been established.
No general differences in safety were observed between patients aged 65 and over and under 65 years of age.
Strong inhibitors and inducers of CYP3A
The use of Osicent should be avoided when using strong CYP3A inhibitors, including macrolide antibiotics (for example, telithromycin), antifungal drugs (for example, itraconazole), antiviral agents (for example, ritonavir), nefazodone, since the concomitant use of strong CYP3A inhibitors may increase the plasma concentration. If no other option exists, patients should be monitored more closely for adverse reactions.
The use of Osicent should be avoided when using strong inducers of CYP3A (eg, phenytoin, rifampicin, carbamazepine, St. John's wort), since strong inducers of CYP3A can reduce the plasma concentration of Osimertinib.
Our online pharmacy delivers Osicent directly from India. All certificates are there! Contracts with manufacturers have been concluded.
We deliver without prepayment!
In the cities: Moscow, St. Petersburg and Krasnodar delivery by courier is possible!
Delivery of medicines from Sofosbuvir Pharmacy is an opportunity to start treatment as soon as possible.
Delivery using the international courier service EMS will help to ensure the quality of the contents of the parcel - we add an inventory of the contents, which makes it possible to open the parcel before receiving it, examine the contents for holograms, coincidence of batch numbers and other data from the package of the medicine. An EMS courier can deliver the parcel to the specified address at a convenient time. If there is no branch in your city, the order can be received at the nearest branch of the Russian Post. Cash on delivery is paid by Sofosbuvir-pharmacy, you only need to pay a commission for the transfer of funds upon receipt - a maximum of 5% of the amount.
If the degree of your trust in Sofosbuvir Pharmacy is so high that you are ready to order prepaid medicines, then we will cover all shipping costs and will also give you a discount for the entire purchase amount. Prepaid delivery can be paid for in any convenient way, and you can get the drugs by EMS courier or at the PR department.
Sofosbuvir Pharmacy has several warehouses in large cities, so we are ready to offer the delivery of medicines by our courier within these cities. Details can be obtained from our specialist on the website or by phone. A pharmacy courier will deliver medicines within 24 hours after ordering.
Sofosbuvir Pharmacy is ready to deliver drugs directly from India. This delivery method requires a full prepayment in the currency that the Indian supplier will call, in addition, you will have to pay a transfer commission of about 10%. Another nuance when delivering from India is a prescription for medicines, it may be required when crossing the border and passing through customs, and an appointment may also be required when receiving medicines by mail. Delivery times from India will be from 10 to 14 days.
Choose the most convenient delivery of drugs from Sofosbuvir-pharmacy, and we will provide high-quality packaging, high quality of the drugs themselves and convenient payment methods!